Human retinoblastoma susceptibility gene: cloning, identification, and sequence, Science, vol.235, pp.1394-1399, 1987. ,
The retinoblastoma tumour suppressor in development and cancer, Nat Rev Cancer, vol.2, pp.910-917, 2002. ,
Retinoblastoma protein partners, Adv Cancer Res, vol.82, pp.1-54, 2001. ,
Retinoblastoma family genes, Oncogene, vol.25, pp.5190-5200, 2006. ,
, Pocket proteins and cell cycle control. Oncogene, vol.24, pp.2796-2809, 2005.
Cell cycle: Retinoblastoma, a trip organizer, Nature, vol.466, pp.1051-1052, 2010. ,
Cellular mechanisms of tumour suppression by the retinoblastoma gene, Nat Rev Cancer, vol.8, pp.671-682, 2008. ,
Evidence for autoregulation and cell signaling pathway regulation from genome-wide binding of the Drosophila retinoblastoma protein, G3, vol.2, pp.1459-1472, 2012. ,
Mutation of E2F-1 suppresses apoptosis and inappropriate S phase entry and extends survival of Rb-deficient mouse embryos, Mol Cell, vol.2, pp.293-304, 1998. ,
-dependent apoptosis produced by Rb-deficiency in the developing mouse lens, Nature, vol.371, pp.72-74, 1994. ,
RB regulates the stability and the apoptotic function of p53 via MDM2, Mol Cell, vol.3, pp.181-193, 1999. ,
Proapoptotic function of the retinoblastoma tumor suppressor protein, Cancer Cell, vol.15, pp.184-194, 2009. ,
Caspase-9 can antagonize p53-induced apoptosis by generating a p76(Rb) truncated form of Rb, Oncogene, vol.24, pp.3297-3308, 2005. ,
URL : https://hal.archives-ouvertes.fr/hal-00101331
Identification and characterization of retinoblastoma gene mutations disturbing apoptosis in human breast cancers, Mol Cancer, vol.9, p.173, 2010. ,
Retinoblastoma tumor suppressor status is a critical determinant of therapeutic response in prostate cancer cells, Cancer research, vol.67, pp.6192-6203, 2007. ,
Radiation-induced apoptosis mediated by retinoblastoma protein, Cancer Res, vol.58, pp.3275-3281, 1998. ,
The retinoblastoma tumor suppressor inhibits cellular proliferation through two distinct mechanisms: inhibition of cell cycle progression and induction of cell death, Oncogene, vol.18, pp.5239-5245, 1999. ,
Evidence for a mitochondrial localization of the retinoblastoma protein, BMC cell biology, vol.10, p.50, 2009. ,
The retinoblastoma protein induces apoptosis directly at the mitochondria, Genes & development, vol.27, pp.1003-1015, 2013. ,
Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis, Embo J, vol.15, pp.6969-6978, 1996. ,
Characterization of interior cleavage of retinoblastoma protein in apoptosis, J Cell Biochem, vol.67, pp.399-408, 1997. ,
The 100-kDa proteolytic fragment of RB is retained predominantly within the nuclear compartment of apoptotic cells, Mol Cell Biol Res Commun, vol.1, pp.216-220, 1999. ,
Caspase-dependent cleavage of the retinoblastoma protein is an early step in neuronal apoptosis, Oncogene, vol.19, pp.2171-2178, 2000. ,
pRb/E2F-1-mediated caspase-dependent induction of Noxa amplifies the apoptotic effects of the Bcl-2/Bcl-xL inhibitor ABT-737, Cell death and differentiation, vol.20, pp.755-764, 2013. ,
URL : https://hal.archives-ouvertes.fr/inserm-02447042
Degradation of Retinoblastoma protein in Tumor Necrosis Factor-and CD95-induced Cell Death, J Biol Chem, vol.272, pp.9613-9616, 1997. ,
-independent dephosphorylation and cleavage of retinoblastoma protein during tamoxifen-induced apoptosis in human breast carcinoma cells, Cancer Lett, vol.130, pp.103-113, 1998. ,
Tumor promotion by caspase-resistant retinoblastoma protein, Proc Natl Acad Sci U S A, vol.102, pp.15587-15592, 2005. ,
The p76(Rb) and p100(Rb) truncated forms of the Rb protein exert antagonistic roles on cell death regulation in human cell lines, Biochemical and biophysical research communications, vol.399, pp.173-178, 2010. ,
Differential regulation of apoptotic genes by Rb in human versus mouse cells, Oncogene, vol.23, pp.2587-2599, 2004. ,
Conserved functions of the pRB and E2F families, Nat Rev Mol Cell Biol, vol.9, pp.713-724, 2008. ,
Emerging roles of E2Fs in cancer: an exit from cell cycle control, Nat Rev Cancer, vol.9, pp.785-797, 2009. ,
Molecular mechanisms of E2F-dependent activation and pRB-mediated repression, J Cell Sci, vol.117, pp.2173-2181, 2004. ,
Cell cycle-dependent and cell cycle-independent control of transcription by the Drosophila E2F/RB pathway, Genes Dev, vol.17, pp.2308-2320, 2003. ,
A gradient of epidermal growth factor receptor signaling determines the sensitivity of rbf1 mutant cells to E2F-dependent apoptosis, Mol Cell Biol, vol.26, pp.7601-7615, 2006. ,
E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage, PLoS Genet, vol.4, p.1000153, 2008. ,
Regulation of apoptosis of rbf mutant cells during Drosophila development, Dev Biol, vol.326, pp.347-356, 2009. ,
The role of RBF in the introduction of G1 regulation during Drosophila embryogenesis, Embo J, vol.18, pp.916-925, 1999. ,
The Drosophila retinoblastoma protein induces apoptosis in proliferating but not in post-mitotic cells, Cell Cycle, vol.9, pp.97-103, 2010. ,
CASVM: web server for SVM-based prediction of caspase substrates cleavage sites, Bioinformatics, vol.23, pp.3241-3243, 2007. ,
SVM-based prediction of caspase substrate cleavage sites, BMC Bioinformatics, vol.7, 2006. ,
The Drosophila caspase DRONC cleaves following glutamate or aspartate and is regulated by DIAP1, HID, and GRIM, J Biol Chem, vol.275, pp.27084-27093, 2000. ,
Activation mechanism and substrate specificity of the Drosophila initiator caspase DRONC, Cell death and differentiation, vol.15, pp.938-945, 2008. ,
The role of Dpp and Wg in compensatory proliferation and in the formation of hyperplastic overgrowths caused by apoptotic cells in the Drosophila wing disc, Development, vol.136, pp.1169-1177, 2009. ,
Regeneration and transdetermination in Drosophila imaginal discs, Annual review of genetics, vol.46, pp.289-310, 2012. ,
The role of apoptosis-induced proliferation for regeneration and cancer, Cold Spring Harbor perspectives in biology, vol.4, p.8797, 2012. ,
Correcting developmental errors by apoptosis: lessons from Drosophila JNK signaling, Apoptosis, vol.14, pp.1021-1028, 2009. ,
Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways, Dev Cell, vol.7, pp.491-501, 2004. ,
Crystal structure of the retinoblastoma protein N domain provides insight into tumor suppression, ligand interaction, and holoprotein architecture, Molecular cell, vol.28, pp.371-385, 2007. ,
Caspase inhibition during apoptosis causes abnormal signalling and developmental aberrations in Drosophila, Development, vol.131, pp.5591-5598, 2004. ,
Dpp signaling and the induction of neoplastic tumors by caspase-inhibited apoptotic cells in Drosophila, Proc Natl Acad Sci U S A, vol.102, pp.17664-17669, 2005. ,
Compensatory proliferation in Drosophila imaginal discs requires Dronc-dependent p53 activity, Curr Biol, vol.16, pp.1606-1615, 2006. ,
Compensatory proliferation induced by cell death in the Drosophila wing disc requires activity of the apical cell death caspase Dronc in a nonapoptotic role, Curr Biol, vol.14, pp.1262-1266, 2004. ,
Compensatory proliferation and apoptosis-induced proliferation: a need for clarification, Cell death and differentiation, vol.20, p.181, 2013. ,
URL : https://hal.archives-ouvertes.fr/ensl-00962316
Tissue homeostasis in the wing disc of Drosophila melanogaster: immediate response to massive damage during development, PLoS genetics, vol.9, p.1003446, 2013. ,