Skip to Main content Skip to Navigation
Journal articles

Structural modifications induced by the mtDBP-C protein in the repfication origin of Xenopus laevis mitochondrial DNA

Abstract : The structure of the non-coding region of Xenopus laevis mitochondrial DNA has been studied by electron microscopy analysis of DNA molecules end-labelled with streptavidin-ferritin. We have shown that the effect of a protein modifying the shape of the DNA double-helix can be studied and precisely located by this method. It was found that the non-coding region contains curved segments and that the mitochondrial protein mtDBP-C preferentially enhances the curvature of the promoters-replication origin region.
Document type :
Journal articles
Complete list of metadata

https://hal.uvsq.fr/hal-03038255
Contributor : Bernard Mignotte Connect in order to contact the contributor
Submitted on : Friday, December 18, 2020 - 4:43:21 PM
Last modification on : Thursday, October 6, 2022 - 10:40:00 AM

Identifiers

  • HAL Id : hal-03038255, version 1

Collections

Citation

Bernard Mignotte, Bernard Theveny, B Revet. Structural modifications induced by the mtDBP-C protein in the repfication origin of Xenopus laevis mitochondrial DNA. Biochimie, Elsevier, 1990, 72, pp.65-72. ⟨hal-03038255⟩

Share

Metrics

Record views

43