Structural modifications induced by the mtDBP-C protein in the repfication origin of Xenopus laevis mitochondrial DNA - Archive ouverte HAL Access content directly
Journal Articles Biochimie Year : 1990

Structural modifications induced by the mtDBP-C protein in the repfication origin of Xenopus laevis mitochondrial DNA

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Abstract

The structure of the non-coding region of Xenopus laevis mitochondrial DNA has been studied by electron microscopy analysis of DNA molecules end-labelled with streptavidin-ferritin. We have shown that the effect of a protein modifying the shape of the DNA double-helix can be studied and precisely located by this method. It was found that the non-coding region contains curved segments and that the mitochondrial protein mtDBP-C preferentially enhances the curvature of the promoters-replication origin region.
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Dates and versions

hal-03038255 , version 1 (18-12-2020)

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  • HAL Id : hal-03038255 , version 1

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Bernard Mignotte, Bernard Theveny, B Revet. Structural modifications induced by the mtDBP-C protein in the repfication origin of Xenopus laevis mitochondrial DNA. Biochimie, 1990, 72, pp.65-72. ⟨hal-03038255⟩
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