Structural modifications induced by the mtDBP-C protein in the repfication origin of Xenopus laevis mitochondrial DNA - Université de Versailles Saint-Quentin-en-Yvelines Access content directly
Journal Articles Biochimie Year : 1990

Structural modifications induced by the mtDBP-C protein in the repfication origin of Xenopus laevis mitochondrial DNA

Abstract

The structure of the non-coding region of Xenopus laevis mitochondrial DNA has been studied by electron microscopy analysis of DNA molecules end-labelled with streptavidin-ferritin. We have shown that the effect of a protein modifying the shape of the DNA double-helix can be studied and precisely located by this method. It was found that the non-coding region contains curved segments and that the mitochondrial protein mtDBP-C preferentially enhances the curvature of the promoters-replication origin region.

Dates and versions

hal-03038255 , version 1 (18-12-2020)

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Bernard Mignotte, Bernard Theveny, B. Revet. Structural modifications induced by the mtDBP-C protein in the repfication origin of Xenopus laevis mitochondrial DNA. Biochimie, 1990, 72 (1), pp.65-72. ⟨10.1016/0300-9084(90)90174-f⟩. ⟨hal-03038255⟩
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