Vaccine strategies against cystic fibrosis pathogens - Université de Versailles Saint-Quentin-en-Yvelines Access content directly
Journal Articles Human Vaccines & Immunotherapeutics Year : 2016

Vaccine strategies against cystic fibrosis pathogens


A great number of cystic fibrosis (CF) pathogens such as Pseudomonas aeruginosa, the Burkholderia cepacia and the Mycobacterium abscessus complex raised difficult therapeutic problems due to their intrinsic multiresistance to numerous antibiotics. Vaccine strategies represent one of the key weapons against these multi-resistant bacteria in a number of clinical settings like CF. Different strategies are considered in order to develop such vaccines, linked either to priming the host response, or by exploiting genomic data derived from the bacterium. Interestingly, virulence factors synthesized by various pathogens might serve as targets for vaccine development and have been, for example, evaluated in the context of CF.
Fichier principal
Vignette du fichier
LeMoigne et human vaccine last version bgm edit.pdf (341.98 Ko) Télécharger le fichier
Origin Files produced by the author(s)

Dates and versions

hal-03680920 , version 1 (31-05-2022)



Vincent Le Moigne, Jean-Louis Gaillard, Jean-Louis Herrmann. Vaccine strategies against cystic fibrosis pathogens. Human Vaccines & Immunotherapeutics, 2016, 12 (3), pp.751 - 756. ⟨10.1080/21645515.2015.1102810⟩. ⟨hal-03680920⟩
39 View
21 Download



Gmail Mastodon Facebook X LinkedIn More