The Novel OMERACT Ultrasound Scoring System for Salivary Gland Changes in Patients With Sjögren Syndrome Is Associated With MRI and Salivary Flow Rates - Université de Versailles Saint-Quentin-en-Yvelines Access content directly
Journal Articles Journal of Rheumatology Year : 2024

The Novel OMERACT Ultrasound Scoring System for Salivary Gland Changes in Patients With Sjögren Syndrome Is Associated With MRI and Salivary Flow Rates

Nevsun Inanc
Kerem Abacar
Çagatay Cimşit
Canan Cimşit
Esperanza Naredo
Alojzija Hocevar
Stephanie Finzel
Carlos Pineda
Helen Keen
Petra Hanova
Wolfgang Schmidt
Gonca Mumcu
Lene Terslev
George Bruyn

Abstract

Objective To assess the construct validity of the novel Outcome Measures in Rheumatology (OMERACT) ultrasound (US) semiquantitative scoring system for morphological lesions in major salivary glands by comparing it with magnetic resonance imaging (MRI) and unstimulated whole salivary flow rates (U-WSFRs) in patients with primary Sjögren syndrome (pSS). Methods Nine sonographers applied the OMERACT 0-3 grayscale scoring system for parotid (PGs) and submandibular glands (SMGs) in 11 patients with pSS who also had MRIs performed. These were evaluated by 2 radiologists using a semiquantitative 0-3 scoring system for morphological lesions. The agreement between US and MRI and the association between U-WSFRs and imaging structural lesions was determined. A score ≥ 2 for both US and MRI was defined as gland pathology. Results The prevalence of US morphological lesions in 11 patients with a score ≥ 2 was 58% for PGs and 76% for SMGs, and 46% and 41% for PGs and SMGs, respectively, for MRI. The agreement between OMERACT US scores and MRI scores was 73-91% (median 82%) in the right PG and 73-91% (median 91%) in the left PG, 55-91% (median 55%) in the right SMG and 55-82% (median 55%) in the left SMG. When relations between the presence of hyposalivation and an US score ≥ 2 were examined, agreement was 91-100% (median 83%) in both PGs and 55-91% (median 67%) in both SMGs. Conclusion There is moderate to strong agreement between the OMERACT US and MRI scores for major salivary glands in patients with pSS. Similar agreement ratios were observed between the higher OMERACT US scores and presence of hyposalivation.

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hal-04551305 , version 1 (18-04-2024)

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Nevsun Inanc, Sandrine Jousse-Joulin, Kerem Abacar, Çagatay Cimşit, Canan Cimşit, et al.. The Novel OMERACT Ultrasound Scoring System for Salivary Gland Changes in Patients With Sjögren Syndrome Is Associated With MRI and Salivary Flow Rates. Journal of Rheumatology, 2024, 51 (3), pp.263-269. ⟨10.3899/jrheum.2023-0202⟩. ⟨hal-04551305⟩
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